Fatigue and Osteoarthritis

Fatigue has been documented as a common complaint in many medical conditions and has been found to be associated with poorer perceived and measured health status. In general, fatigue associated with medical illness is ascribed to tissue destruction, infection, inflammation or malignancy. Fatigue in OA is not routinely evaluated and has only been considered in a limited number of studies. However, this does not negate the significance of fatigue in OA. Fatigue in inflammatory rheumatic disorders has been found to be associated with pain, poor sleep quality and psychological factors such as depression, anxiety, stress and helplessness. Complicating the study of pain and fatigue in OA is the fact that many of the symptoms of OA may over lap with those of depression. Further, measures of depression include items that may also be found in measures of fatigue (eg. lack of energy). In order to thoroughly understand fatigue in OA, it is necessary to consider the multi-dimensional nature of fatigue and to determine if pain, fatigue and depression represent distinct or hybrid constructs. This project is evaluating the relationship between pain, depression and fatigue with osteoarthritis disability.

Investigators

J. Denise Power (PhD thesis), Elizabeth Badley, Gillian Hawker

Date

2005+
  • Power DJ, Badley EM, French MR, Wall AJ, Hawker GA. Fatigue in osteoarthritis: a qualitative study. BMC Musculoskeletal Disorders. 2008 May 1; 9(1): 63 [Epub ahead of print]
  • Power JD, Badley EM, Hawker GA. The Multi-Dimensional Nature of Fatigue in Osteoarthritis. Arthritis Rheum 2007; 56 (9): S506.
  • Power JD, Badley EM, Hawker GA. The Multi-Dimensional Nature of Fatigue in Osteoarthritis. Poster presentation to the 2007 Annual Scientific Meeting of the American College of Rheumatology; Nov 6-11, Boston, 2007.
  • Power JD, French M, Badley EM, Hawker GA. The Fatigue Experience in Osteoarthritis. Accepted as an oral presentation to the 2006 Annual Scientific Meeting of the American College of Rheumatology and the Association of Rheumatology Health Professionals; Nov 10-15, 2006, Washington, DC.
  • Power JD, Hawker GA, Badley EM. Fatigue in Osteoarthritis. (Poster) Society for Epidemiologic Research (SER), the 2nd North American Congress of Epidemiology, 21-24 June 2006, Seattle, Washington.
Last modified: June 13, 2008